🟡 Rationale: Jaundice 🟡

Jaundice is a condition in which the skin and the whites of the eyes appear yellow.

This condition occurs when the amount of bilirubin in the body becomes higher than normal.

The question is – Which substance accumulates in the skin and sclera in jaundice?

✅ Correct Answer: (c) both bilirubin and bilirubin diglucuronide

In jaundice, bilirubin (whether it is unconjugated or conjugated bilirubin (bilirubin diglucuronide)) increases in the blood.

This increased bilirubin gets deposited in the skin and sclera, causing the yellow discoloration.

Therefore, the substance that accumulates in jaundice is → bilirubin (in both forms).

Why are the other options incorrect?

(a) Unconjugated bilirubin → This is only one type, whereas in jaundice both types can accumulate.

(b) Direct bilirubin → This is also an incomplete answer, because only direct bilirubin is not responsible.

(d) Biliverdin → This is a precursor of bile pigment, but it does not accumulate in the skin in jaundice.

✅ Exam Point:
Substance deposited in the skin & sclera in Jaundice →
➤ Bilirubin (conjugated + unconjugated)
(Anatomy & Medical-Surgical Nursing)

📌 Disclaimer: This material is for nursing exam preparation only. For clinical practice, follow standard textbooks.

💚 Exam Objective Nursing – Asha D
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