Rationale: Excess Secretion of Growth Hormone

Growth Hormone (GH) is secreted by the anterior pituitary gland. This hormone is extremely important for the body’s height, bone growth, and overall development.

When the secretion of Growth Hormone becomes higher than normal, its effects depend on the state of the epiphyseal plate.

If excessive Growth Hormone secretion occurs before the epiphyseal plate closes, there is excessive increase in bone length, which is called Gigantism.

However, if excessive Growth Hormone secretion occurs after the epiphyseal plate closes, the bones do not increase in length. Instead, the hands, feet, jaw, and facial bones become thicker and larger. This condition is called Acromegaly.

Therefore, excessive secretion of Growth Hormone can lead to Gigantism and Acromegaly, depending on the timing of hormone excess.

Cretinism is not related to Growth Hormone. It is caused by deficiency of thyroid hormone.

✅ Exam Point:
Excessive secretion of Growth Hormone
➤ Before epiphyseal plate closure → Gigantism
➤ After epiphyseal plate closure → Acromegaly
Hence, the correct concept is: Both A and B

📌 Disclaimer: This information is for nursing exam preparation and educational purposes only. For actual clinical decisions, refer to standard physiology and endocrinology textbooks.

💚 Exam Objective Nursing – Asha D
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